Bone tissue engineering becomes a reality
A*STAR researchers have developed small biodegradable and biocompatible supports that aid stem cell differentiation and multiplication as well as bone formation in living animal models. Existing approaches to expand stem cells for industrial applications tend to use two-dimensional materials as culture media, but their production yields are too low for clinical demand. However, researchers at A*STAR Bioprocessing Technology Institute, in collaboration with the A*STAR Institute of Materials Research and Engineering, have created directly implantable microscopic spheres. These spheres support scalable and cost-effective stem cell expansion and bone formation for tissue engineering. The team now plans to further investigate the therapeutic potential of these microcarrier–stem cell assemblies in actual bone healing models.
Read the full press release here.
Mewburn Ellis partner Richard Clegg has been working closely with A*STAR on this technology. He and his team advise A*STAR on their IP strategy and building and defending of their IP portfolio.